However, since the crop types which are included in the category of ornamentals is not defined, EFSA did not consider that the available risk assessments would cover the risk, when it is assessed with the EFSA guidance document (EFSA, 2013) from the outdoor use on ornamentals (data gap).1212 An indoor microcosm study was also available with the representative formulation. For the outdoor uses in ornamentals, a low risk is indicated for the R2/R3 FOCUS scenarios at Step 4, provided that 10 m buffer/50% spray reduction is used. Full details of the Good Agricultural Practices (GAPs) can be found in the list of end points in Appendix A. Refer to experts’ consultation 2.5 in the Report of Pesticides Peer Review Experts’ Meeting 190 (EFSA, 2019). In addition, the consumer risk assessment is not finalised considering the lack of appropriate information to address the effect of water treatment processes on the nature of residues potentially present in surface water, when surface water is abstracted for drinking (see Sections, The chronic risk assessment to aquatic invertebrates for the pertinent aquatic metabolite PYPAC, could not be finalised (see Sections, The risk assessment to sediment‐dwelling organisms from exposure via the sediment could not be finalised (see Sections, The risk assessment for bees from the field use on ornamentals (see Section, The risk assessment for sublethal effects to honeybees could not be concluded (see Section, The superscript numbers relate to the numbered points indicated in Sections, Collaborative International Pesticides Analytical Council Limited, period required for 50% dissipation (define method of estimation), period required for 90% dissipation (define method of estimation), Oestrogen, androgen, thyroid or steroidogenic, Food and Agriculture Organization of the United Nations, Forum for the Co‐ordination of Pesticide Fate Models and their Use, high‐pressure liquid chromatography with tandem mass spectrometry, International Organization for Standardization, International Union of Pure and Applied Chemistry, Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues (Joint Meeting on Pesticide Residues), Freundlich organic carbon adsorption coefficient, liquid chromatography with tandem mass spectrometry, Organisation for Economic Co‐operation and Development, predicted environmental concentration in air, predicted environmental concentration in groundwater, predicted environmental concentration in sediment, predicted environmental concentration in soil, predicted environmental concentration in surface water, pF value of 2 (suction pressure that defines field capacity soil moisture), quantitative structure–activity relationship, simplified molecular‐input line‐entry system. With regard to the assessment of the ED potential of pyriproxyfen according to the ECHA and EFSA (2018), two fish short‐term reproduction assays (level 3 study) and a fish full life cycle test with Medaka were available. Finally, the consumer risk assessment is not finalised with regard to the unknown nature of residues that might be present in drinking water, consequent to water treatment processes following abstraction of surface water that might contain pyriproxyfen and its metabolites (see Section 4). ). $48.94 $ 48. No assessment was available for puddle water; however, the risk from this scenario was also considered as low on the basis of the risk assessment for guttation water. 4.5 out of 5 stars 29. It is primarily used to fight pests in a number of crops. In addition to the acute data, appropriate chronic data were available for adult honeybees and larvae with the active substance. A risk assessment for the sediment compartment (using FOCUS PECsed values) was not available although it is triggered,1111 buffer zones and/or spray drift reduction (FOCUS Step 4). PECsw for pyriproxyfen and metabolites 4’‐OH‐Pyr and PYPAC were calculated for closed walk‐in tunnels based on Step 3 drainage scenarios and for the use in high technology greenhouses, the specific model GEM (version 3.3.2) was used for both soil‐bound and soil‐less scenarios. Pyriproxyfen 10% EC. Apply Pivot 10 solution wherever conditions could support insect populations. 1-16 of 108 results for "Pyriproxyfen" Skip to main search results Eligible for Free Shipping. In addition, a key supporting document to this conclusion is the peer review report (EFSA, By continuing to browse this site, you agree to its use of cookies as described in our, I have read and accept the Wiley Online Library Terms and Conditions of Use, Guidance for the identification of endocrine disruptors in the context of Regulations (EU) No 528/2012 and (EC) No 1107/2009, Opinion on a request from EFSA related to the default Q10 value used to describe the temperature effect on transformation rates of pesticides in soil, Guidance on Risk Assessment for Birds and Mammals on request from EFSA, Submission of scientific peer‐reviewed open literature for the approval of pesticide active substances under Regulation (EC) No 1107/2009, EFSA Guidance Document on the risk assessment of plant protection products on bees (, EFSA Guidance Document for evaluating laboratory and field dissipation studies to obtain DegT50 values of active substances of plant protection products and transformation products of these active substances in soil, Guidance on the assessment of exposure of operators, workers, residents and bystanders in risk assessment for plant protection products, Peer review report to the conclusion regarding the peer review of the pesticide risk assessment of the active substance pyriproxyfen, Guidance on tiered risk assessment for plant protection products for aquatic organisms in edge‐of‐field surface waters, Residues: guidance for generating and reporting methods of analysis in support of pre‐registration data requirements for Annex II (Part A, Section 4) and Annex III (Part A, Section 5) of Directive 91/414, Technical material and preparations: guidance for generating and reporting methods of analysis in support of pre‐ and post‐registration data requirements for Annex II (Part A, Section 4) and Annex III (Part A, Section 5) of Directive 91/414, Guidance Document on Terrestrial Ecotoxicology Under Council Directive 91/414/EEC, Guidance Document on Aquatic Ecotoxicology Under Council Directive 91/414/EEC, Guidance Document on Assessment of the Relevance of Metabolites in Groundwater of Substances Regulated under Council Directive 91/414/EEC, Guidance Document on residue analytical methods, Review report for the active substance pyriproxyfen, Guidelines on comparability, extrapolation, group tolerances and data requirements for setting MRLs, Guidance document on the assessment of the equivalence of technical materials of substances regulated under Regulation (EC) No 1107/2009, Assessing potential for movement of active substances and their metabolites to ground water in the EU. Considering the high margin of safety this would not trigger a concern in mammalian toxicology, in residues and in soil compartment assessment for the representative uses evaluated. 15% AR in sediment), PYPAC (max. For the representative uses in citrus, ornamentals and tomatoes, a low in‐field risk was concluded only for O. laevigatus. For ruminants and for both labellings, pyriproxyfen was extensively degraded in milk, liver and kidney (< 1–15% TRR) with 4’‐OH‐PYR (free and sulfate conjugates) being predominant in those matrices (18–53% TRR), 2,5‐OH‐PY (conjugate) in milk (30% TRR), POPA in liver (16% TRR) and POP sulfate conjugate in kidney (36% TRR). A low risk to sediment‐dwelling organisms could not be concluded for the exposure via the sediment. On the basis of the available data, high in‐field risk was indicated for T. pyri for the representative uses in pome fruit, citrus, ornamentals and tomatoes. All other components of the residue were below 10% TRR. These mitigation measures applied at Step 4 modelling included no‐spray drift buffer zones of up to 30 m for the field uses. OJ L 309, 24.11.2009, p. 1–50. Data were submitted to conclude that the use of pyriproxyfen according to the representative uses proposed at EU level results in a sufficient insecticidal efficacy against the target organisms, following the guidance document SANCO/2012/11251‐rev. However, a high risk to T. pyri could not be excluded. This has led to the identification of a data gap (see Section 7) and results in the consumer risk assessment not being finalised (see Section 9). For the uses in pome fruit (early), a high chronic risk to fish cannot be excluded for the D5/R2/R3 FOCUS scenarios at Step 4. It is also used as a prevention for flea control on household pets, for killing indoor and outdoor ants and roaches. For the rabbit developmental toxicity, the maternal NOAEL was 100 mg/kg bw per day based on increased abortions and/or premature deliveries. 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